BDBM50527154 CHEMBL4454255

SMILES Cc1nc2cc(nn2c(-c2cc(F)c3OCCCc3c2C)c1[C@H](OC(C)(C)C)C(O)=O)-c1ccccc1

InChI Key InChIKey=TZXRURYHFBZSGH-MHZLTWQESA-N

Data  1 KI  1 EC50

PDB links: 2 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50527154   

TargetIntegrase(Human immunodeficiency virus 1)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50527154(CHEMBL4454255)
Affinity DataKi:  90nMAssay Description:Allosteric inhibition of [3H]-2-tert-butoxy-2-[2-methyl-4-(p-tolyl)-3-quinolyl]acetic acid binding to HIV1 integrase measured after 1 hr under dark c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50527154(CHEMBL4454255)
Affinity DataEC50:  5.70E+3nMAssay Description:Transactivation of human PXR transfected in human HepG2 cells co-transfected with CYP3A4-Luc plasmid incubated for overnight by luciferase reporter g...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB